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Compound InformationSONAR Target prediction
Name:

Minocycline hydrochloride

Unique Identifier:LOPAC 00607
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:C24ClH29N2O7
Molecular Weight:465.735 g/mol
X log p:4.163  (online calculus)
Lipinksi Failures0
TPSA54.45
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:9
Rotatable Bond Count:3
Canonical Smiles:Cl.CC(C)C1C2CC3Cc4c(ccc(O)c4C(=O)C3=C(O)C2(O)C(=O)C(C(N)=O)=C1O)N(C)C
Class:Cell Cycle
Action:Inhibitor

Found: 24 nonactive as graph: single | with analogs 1 2 3 4 5 6 7 8 9 10  Next >> [24]
Species: 4932
Condition: BY4741
Replicates: 8
Raw OD Value: r im 0.7669±0.075407
Normalized OD Score: sc h 0.9852±0.015966
Z-Score: -0.6477±0.533741
p-Value: 0.518648
Z-Factor: -135.372
Fitness Defect: 0.6565
Bioactivity Statement: Nonactive
Experimental Conditions
Library:Lopac
Plate Number and Position:11|A3
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:27.80 Celcius
Date:2005-04-07 YYYY-MM-DD
Plate CH Control (+):0.04756875±0.00100
Plate DMSO Control (-):0.7615562500000002±0.04256
Plate Z-Factor:0.8396
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DBLink | Rows returned: 0

internal high similarity DBLink | Rows returned: 0

active | Cluster 12393 | Additional Members: 20 | Rows returned: 4
Prest1244 0.490196078431373
Prest1045 0.452631578947368
SPE01505684 0.452631578947368
Prest60 0

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